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目的探讨胃癌术后早期肠内营养(EEN)对机体恢复的影响。方法将40例胃癌且伴有营养不良患者行根治性手术后随机分为两组,肠内营养(EN)组术后1~2d开始EN治疗,肠外营养(PN)组术后24h经外周静脉输入由葡萄糖、脂肪乳剂、氨基酸等配置的全营养混合液。两组患者营养支持持续1周,逐渐恢复进食。观察两组患者并发症的发生率、术后肠功能恢复时间及住院时间及所需费用。结果 EN组排气恢复时间、术后住院天数及住院费用均少于PN组,差异有统计学意义(P<0.05)。各组并发症发生率比较,差异无统计学意义(P>0.05);EN组并发症发生率为22.2%,低于PN组的45.5%,差异有统计学意义(P<0.05)。结论胃癌根治术后EEN支持是安全、合理、有效的营养补给方式;与PN支持相比更有利于患者营养状态的恢复及肛门排气功能的恢复,且经济方便。
Objective To investigate the effect of early postoperative enteral nutrition (EEN) on recovery in patients with gastric cancer. Methods Forty patients with gastric cancer and malnutrition were randomly divided into two groups: enteral nutrition group (EN) 1 ~ 2 days after operation and PN group Intravenous infusion of glucose, fat emulsion, amino acids, such as the allocation of full nutrition mixture. Nutritional support in both groups lasted for 1 week and gradually recovered. The incidence of complications, the time of recovery of intestinal function after operation and the length of hospital stay and the required costs were observed. Results The exhaust recovery time, postoperative hospitalization days and hospitalization costs of EN group were less than those of PN group, with significant difference (P <0.05). There was no significant difference in complication rates between the two groups (P> 0.05). The incidence of complications in EN group was 22.2%, which was lower than 45.5% in PN group (P <0.05). Conclusion EEN support after radical operation of gastric cancer is a safe, reasonable and effective way of nutritional supplementation. Compared with PN support, it is more conducive to the recovery of nutritional status and the recovery of anal exhaust function, and is economical and convenient.