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[Objective] To establish good animal models of hepatocellular carcinoma (HCC) and serve treatment of HCC in humans. [Method] Several common animal models of HCC were introduced briefly. [Result] The commonly used animal models include C57BL/6J mouse model of orthotopic HCC induced with Hepa1-6 cells, nude mouse model of HCC constructed with Hep_G2 cell lines, rat HCC model constructed through direct transplantation or direct injection, HU-PBL-SCID mice model, and other transplanted HCC models or genetic HCC models. [Conclusion] Animal model is an important means and platform for experimental studies. To establish animal models of HCC is of important significance for studies on pathogenesis, diagnosis and treatment of HCC.
[Objective] To establish good animal models of hepatocellular carcinoma (HCC) and serve treatment of HCC in humans. [Method] Several common animal models of HCC were introduced briefly. [Result] The commonly used animal models include C57BL / 6J mouse model of orthotopic HCC induced with Hepa 1-6 cells, nude mouse model of HCC constructed with Hep_G2 cell lines, rat HCC model constructed through direct transplantation or direct injection, HU-PBL-SCID mice model, and other transplanted HCC models or genetic HCC models. [ To establish animal models of HCC is of important significance for studies on pathogenesis, diagnosis and treatment of HCC.