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目的:探讨老年人巨幼细胞性贫血(megaloblastie anemia,MBA)的临床特点。方法:对180例老年人MBA住院患者的资料进行回顾性分析。结果:老年人MBA男性多于女性;多伴有心、脑血管等内科其他疾病,易于漏诊;外周血三系细胞可出现不同程度的减少;病因MBA以消化道疾病居多,HP感染率高;多存在诱发因素;确诊后予叶酸,维生索B12治疗后预后良好。结论:老年人MBA比较常见但常因非血液病就诊而易于漏诊,积极治疗原发病,尤其是消化道疾病,改善饮食结构,供给富含叶酸、维生素B12的食物,定期进行体检也是预防老年MBA不可忽视的重要措施。
Objective: To investigate the clinical features of megaloblastie anemia (MBA) in the elderly. Methods: A retrospective analysis of 180 elderly MBA inpatients. Results: There were more MBA males than females in the elderly, more often accompanied by other internal diseases such as heart and cerebrovascular diseases, which were easily missed by diagnosis. The peripheral blood mononuclear cells could be reduced in varying degrees. The causes of the disease were mostly gastrointestinal diseases and HP infection rates. There are predisposing factors; diagnosis of folic acid, vitamin B12 treatment after a good prognosis. Conclusion: The elderly MBA is more common but often missed due to non-hematological disease, active treatment of primary disease, especially gastrointestinal diseases, improve diet, food rich in folic acid and vitamin B12, and regular medical examination is also to prevent the elderly MBA can not be ignored important measures.