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目的观察泮托拉唑治疗十二指肠溃疡的临床效果。方法选取医院收治的十二指肠溃疡患者135例作为研究对象,随机分为观察组(68例)和对照组(67例)。观察组采用泮托拉唑药物治疗,对照组采用奥美拉唑药物治疗。观察2组临床治疗效果、不良反应发生情况及患者完成3d治疗后疼痛改善情况。结果 2组治疗总有效率、不良反应发生率比较,差异均无统计学意义(P>0.05)。完成3d治疗后,观察组疼痛感消失率为80.88%,高于对照组的64.18%(P<0.05)。结论十二指肠溃疡患者临床选用泮托拉唑及奥美拉唑治疗,两者临床疗效较为一致,但采用泮托拉唑治疗可在短时间内有效缓解疼痛症状,综合分析泮托拉唑的应用价值更为显著。
Objective To observe the clinical effect of pantoprazole in the treatment of duodenal ulcer. Methods A total of 135 patients with duodenal ulcer admitted to hospital were enrolled in the study. They were randomly divided into observation group (68 cases) and control group (67 cases). The observation group was treated with pantoprazole, while the control group was treated with omeprazole. The effects of clinical treatment, adverse reactions and improvement of pain in patients after 3d treatment were observed. Results The total effective rate of treatment, the incidence of adverse reactions, the difference was not statistically significant (P> 0.05). After 3d treatment, the disappearance rate of pain in the observation group was 80.88%, which was higher than that in the control group (64.18%, P <0.05). Conclusions The clinical efficacy of pantoprazole and omeprazole in patients with duodenal ulcer is better than that of pantoprazole. However, the treatment with pantoprazole can effectively relieve the pain symptoms in a short period of time. A comprehensive analysis of pantoprazole The application value is more significant.