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采用ＥＬＩＳＡ夹心法，对急性肝炎和慢性肝赃疾病患者的血清可溶性白细胞介素２受体（ＳＩＬ－２Ｒ）进行检测，以健康献血员作为对用。结果显示，急性肝炎和慢性活动性乙肝患者血清ＳＩＬ－２Ｒ含量明显高于对照用（Ｐ＜０．０１）；提示急、慢性肝炎病人存在着免疫学异常。肝炎后肝硬化患者血清ＳＩＬ－２Ｒ与对照组无显著性差异（Ｐ＞０．０５），与肝功能分级关系密切。
Serum soluble interleukin-2 receptor (SIL-2R) in patients with acute hepatitis and chronic hepatic diseases was detected by ELISA sandwich method, and healthy blood donors were used as a reference. The results showed that serum SIL-2R levels in patients with acute hepatitis and chronic active hepatitis B were significantly higher than those in the control (P <0.01), suggesting that immunological abnormalities existed in acute and chronic hepatitis patients. Serum SIL-2R in patients with posthepatitic cirrhosis was not significantly different from that in the control group (P> 0.05), which was closely related to the grading of liver function.