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1991年8月1例71岁的老妇(其它方面均健康)由于直肠癌引起的肠梗阻接受了急诊Hartmann手术。1年后她又接受了造口旁疝修补术,直到1995年9月一直处于无症状无疾病状态。1995年9月在造口周围皮肤发现水疱及脱屑样皮损,起初认为是由少量的造口漏出物刺激引起的,一肠造口治疗师对其皮损进行了局部治疗。2个月后皮损复发。于是病人被送至一皮肤病学家处。在典型的病理学及直接免疫荧光学研究的基础上被诊断为大疱性类天疱疮。病人经过了口服四环素(500mg×2次/d)2个月及短期(2周)的皮质类固醇激素治疗,其皮损彻底愈合无复发直到现在。
In August 1991, a 71-year-old woman (otherwise healthy) received emergency Hartmann surgery for bowel obstruction caused by rectal cancer. One year later, she accepted a parasellar hernia repair until September 1995. She was asymptomatic and disease-free. In September 1995, blisters and desquamative skin lesions were found on the skin around the stoma, which was originally thought to have been caused by a small amount of stoma leakage, and a gut stump therapist treated the lesion locally. Recurrence of skin lesions after 2 months. The patient was then sent to a dermatologist. Based on a typical pathology and direct immunofluorescence study, it was diagnosed as bullous pemphigoid. The patient received corticosteroid therapy with oral tetracycline (500 mg x 2 times/d) for 2 months and short-term (2 weeks). Her skin lesions healed without recurrence until now.