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目的：为观察放疗联合双侧髂内动脉插管化疗药物灌注及栓塞治疗骨盆内恶性肿瘤的疗效。方法：对３２例恶性骨盆肿瘤进行了放疗联合经一侧股动脉穿刺插管双侧髂内动脉灌注化疗药物及生物制剂并进行栓塞，放疗采用盆腔野照射４５～５０Ｇｙ／８～１０周，介入治疗３～４周进行１次，每２次１疗程，放疗疗程与介入疗程交替进行。结果：３２例患者共１０５次介入治疗，最少１次，最多８次，平均３２８次。ＣＲ２例，ＰＲ１２例，ＭＲ１０例，ＳＤ２例，ＰＤ４例，无法评价疗效２例。有效率（ＣＲ＋ＰＲ）为４６６％（１４／３０）。半年存活２６例，占８６７％；１ａ存活２１例，占７００％；２ａ存活８例，占２６％。４例获得二次手术机会。结论：髂内动脉药物灌注及栓塞术联合放疗对中晚期恶性骨盆肿瘤可限制发展，减轻症状，延长生命，为一种有效的姑息疗法
OBJECTIVE: To observe the efficacy of radiotherapy combined with bilateral intra-arterial infusion of chemotherapy drugs and embolization for the treatment of pelvic malignant tumors. METHODS: Thirty-two malignant pelvic tumors were treated with radiotherapy combined with bilateral internal iliac arterial infusion of chemotherapeutic drugs and biologics and embolization. Radiotherapy was performed using pelvic field irradiation for 45-50 Gy for 8 to 10 weeks. The treatment is performed once every 3 to 4 weeks, every 2 times for one course of treatment, alternating between radiotherapy and interventional treatment. RESULTS: A total of 105 interventions were performed in 32 patients, at least once and at most 8 times, with an average of 3 28 times. There were 2 cases of CR, 12 cases of PR, 10 cases of MR, 2 cases of SD, and 4 cases of PD. Two cases could not be evaluated for efficacy. The effective rate (CR+PR) was 46.6% (14/30). Half a year survived 26 cases, accounting for 86.7%; 1a survived 21 cases, accounting for 70.0%; 2a survived 8 cases, accounting for 26%. Four patients received secondary surgery. Conclusion: The intra-iliac arterial drug infusion and embolization combined with radiotherapy can restrict the development of advanced malignant pelvic tumors, reduce symptoms, and prolong life. It is an effective palliative therapy.