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目的研究右旋糖酐-40联合复方丹参注射液治疗妊娠晚期羊水过少的临床疗效。方法选取该院在2013年8月-2014年8月间收治的56例妊娠晚期羊水过少病例的临床资料根据数字随机分组法,将患者分为两组,每组各28例。对照组采用常规静脉输液治疗,观察组采用右旋糖酐-40联合复方丹参注射液治疗,比较两组孕妇的血浆比黏度、血小板黏附率、S/D值、羊水指数(AFI)、最大羊水(AFV)指标与妊娠结局。结果 1治疗后,与对照组相较,观察组的相关指标改善情况更好,两组对比差异有统计学意义(P<0.05)。2观察组低轻度窒息率、剖宫产率低于对照组,差异有统计学意义(P<0.05)。3观察组产后出血量更低,新生儿体重更高,两组对比差异有统计学意义(P<0.05)。结论右旋糖酐-40联合复方丹参注射液对妊娠晚期羊水过少患者进行治疗,可以促使血黏度降低,将血小板聚集减少,使围生儿生存率提升,能够取得较好的疗效,值得临床推广应用。
Objective To study the clinical efficacy of dextran-40 combined with Salvia miltiorrhiza in the treatment of oligohydramnios in late pregnancy. Methods The clinical data of 56 cases of oligohydramnios in late pregnancy were collected from August 2013 to August 2014 in our hospital. According to the digital randomization method, the patients were divided into two groups, 28 cases in each group. The control group was treated with routine intravenous infusion. The observation group was treated with dextran-40 combined with compound Salvia miltiorrhiza injection. The plasma specific viscosity, platelet adhesion rate, S / D, amniotic fluid index (AFI), maximum amniotic fluid (AFV) Indicators and pregnancy outcomes. Results 1 After treatment, compared with the control group, the observation group improved the relevant indicators better, the difference between the two groups was statistically significant (P <0.05). The rate of cesarean section in the observation group was lower than that in the control group, the difference was statistically significant (P <0.05). The observation group had lower postpartum hemorrhage and higher birth weight, the difference between the two groups was statistically significant (P <0.05). Conclusion Dextran-40 combined with Salvia miltiorrhiza injection for the treatment of patients with oligohydramnios in the third trimester of pregnancy can reduce the blood viscosity, reduce the platelet aggregation, improve the survival rate of perinatal children and achieve better curative effect, which is worthy of clinical application.