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为了证实血液和尿液N-乙酰-β-氨基葡萄糖苷酶(NAG,EC 3.2.1.30)同工酶是否能为糖尿病状态及其并发症的诊断提供资料,本文作者用Whiting,Dance 等的方法以及离子交换层析,分别测定了40名(年龄19～72岁)糖尿病患者、30名(年龄21～64岁)健康对照受检者血清和尿液的总NAG 活性及其主要同工酶A 和B 的浓度。实验时,将糖尿病患者分为两组。第1组由20名稳定的、无血管损伤的胰岛素依赖型糖尿病患者组成:本组患者患病时间不足5年。第2组由20名稳定的、伴有血管并发症的胰岛素依赖型糖尿病患者组成,其患病时间平均为10年(范围6～18年)。测定结果见表一和表二。
To confirm whether blood and urine N-acetyl-β-glucosaminidase (NAG, EC 3.2.1.30) isoenzymes provide information on the diagnosis of diabetic conditions and their complications, the authors used methods such as Whiting, Dance et al. And ion exchange chromatography were used to measure the total NAG activity and the activities of major isoenzymes A and B in serum and urine of 40 healthy subjects (aged 19 to 72 years) and 30 healthy controls (aged 21 to 64 years) And B concentration. During the experiment, patients with diabetes were divided into two groups. Group 1 consisted of 20 stable, nonvascular diabetic patients with insulin-dependent diabetes: The group had less than 5 years of illness. Group 2 consisted of 20 stable, insulin-dependent diabetic patients with vascular complications with an average duration of disease of 10 years (range, 6 to 18 years). The results are shown in Table 1 and Table II.