【摘 要】
：
Objective To investigate the association between the plasminogen activator inhibitor-1 (PAI-1) 4G/5G gene polymorphism and the occurrence of myocardial and cere
【机 构】
：
State Key Laboratory of Experimental Hematology
论文部分内容阅读
Objective To investigate the association between the plasminogen activator inhibitor-1 (PAI-1) 4G/5G gene polymorphism and the occurrence of myocardial and cerebrovascular infarctions in individuals from Tianjin, China.Methods The PAI-1 genotype was determined using allele-specific polymerase chain reaction (AS-PCR) in 56 myocardial infarction (MI) patients, 54 cerebrovascular infarction(CI) patients and 83 unrelated healthy controls. All subjects clinical features and plasma PAI-1 activity levels were determined.Results The PAI-1 genotype distribution frequency of the single guanine deletion/insertion 4G/5G polymorphism (located -675 bp upstream from the start of transcription) significantly differed between the patients and healthy controls. In the MI group, the 4G/4G-genotype frequency was increased, but the 4G/5G-genotype is decreased when compared to the control group. In the CI group, both the 4G/4G- and 4G/5G -genotypes occurred at a lower frequency than those in the control group (P
其他文献
对超声波热量表进行了耐久性试验,发现了引起超声波热量表失效的5种情况.超声波换能器失效、塑料测量管或塑料超声反射片安装支架失效、积算器失效、管道密封失效和温度传感
根据ISO 7278-3:1998标准,讨论了双计时脉冲插值原理,推导了有关公式.基于双计时脉冲插值原理,以Ahera Cyclone Ⅱ系列的EP2C5T144C8 FPGA为核心器件,设计了具有双计时脉冲插
设计了一种电控线性旋转流量阀,此阀门采用步进电机控制,具有较好的重复性.通过Matlab初步拟合出阀芯过流曲线,满足阀芯旋转角度与过流面积的线性对应关系;利用SolidWords画
介绍了一种称为射流流量计的新型家用燃气表,该流量计用数片带有流通孔的不同厚度和形状的双稳态射流元件叠加,组成可产生射流振荡的测量元件,将流量信号转换成脉冲信号输出,
斜纹夜蛾食性杂,为害蔬菜、甘薯、花生等多种农作物,具有暴食性,喜高温环境,全年危害高峰在夏季。世代重叠,繁殖力强,每雌虫能产卵1000多粒,幼虫初群集取食,3龄后转株为害,高
Monitoring of soil nitrogen (N) cycling is useful to assess soil quality and to gauge the sustainability of management practices.We studied net N mineralization
Objective To investigate whether pretreatment with α1,-antitrypsin (AAT) can attenuate acute lung injury (ALI) in rabbits induced with endotoxin.Methods Thirt
Objective To detect the expression of cytokines by acute promyelocytic leukemia (APL) cells before and after exposure to arsenic trioxide.Methods Diagnoses wer
Objective To determine whether the extent of prolongation of the transisthmus interval after ablation predicts complete bidirectional block. Methods Since 1996
Objective To investigate the effects of BmkTXKβ, a newly purified ‘long chain peptide inhibitor of K+ channels from the Chinese scorpion Buthus martensi Karsc