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本文以雄性Wistar大鼠的ALA-D活性作为一种实验模型研究了铅及其在生物学系统中与其它成分的相互作用。腹腔注射1mg/kg铅的大鼠在30分钟、1、2、3和4小时后立即处死。结果表明铅在注入大鼠体内后立即直接影响酶分子,首先作用于锌的活性位置然后作用于巯基。不耐热因子的诱导似乎出现较迟,
In this paper, ALA-D activity in male Wistar rats was used as an experimental model to study the interaction of lead and its interaction with other components in the biological system. Rats given ip at 1 mg / kg were sacrificed immediately after 30 minutes, 1, 2, 3 and 4 hours. The results showed that lead directly affects the enzyme molecule immediately after injection into the rat body, acting first on the active site of zinc and then on the thiol group. The induction of thermolabile appears to be late,