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目的:评价放射治疗对骨转移癌的止痛效果。方法:对115 例骨转移癌患者,202处转移病灶进行单纯放射治疗,其中106处病灶2 Gy/次,5 次/周照射,总剂量36 Gy ~ 54 Gy;67处病灶3 Gy/次,5 次/周照射,总剂量30 Gy ~ 42 Gy;29处病灶4 Gy/次,5 次/周照射,总剂量20 Gy ~ 24 Gy。结果:总有效率97.5 %(197/202),其中疼痛完全缓解率78.2 %(158/202);部分缓解率19.3 %(39/202),不同剂量分割组间和原发灶控制与否,止痛疗效差异无显著性。结论:骨转移癌的放射治疗止痛效果确切,不仅大部分患者可以获得较持久的止痛疗效,而且保持满意的生活质量。
Objective: To evaluate the analgesic effect of radiotherapy on bone metastases. Methods: One hundred and fifteen patients with metastatic bone cancer and 202 metastatic lesions were treated with radiotherapy alone. 106 lesions were treated with 2 Gy / time and 5 cycles / week, with a total dose of 36 Gy ~ 54 Gy; 67 lesions of 3 Gy / 5 times / week irradiation, the total dose of 30 Gy ~ 42 Gy; 29 lesions 4 Gy / time, 5 times / week irradiation, the total dose of 20 Gy ~ 24 Gy. Results: The total effective rate was 97.5% (197/202), the complete pain relief rate was 78.2% (158/202); the partial response rate was 19.3% (39/202) No significant difference in analgesic efficacy. CONCLUSIONS: Radiotherapy for bone metastases has a pain-relieving effect and not only does the majority of patients achieve longer lasting analgesia but maintains a satisfactory quality of life.