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目的探讨糖尿病并发消化性溃疡的病因、临床特点及治疗。方法对65例糖尿病并发消化性溃疡患者的临床资料进行回顾性分析,包括患者的电子胃镜检查、幽门螺杆菌(Hp)感染检测及病理检查等资料。结果糖尿病并发消化性溃疡患者的临床症状不典型,溃疡发生率及病情与糖尿病病程长短有关,发病年龄较高。65例患者治愈41例(63.1%),好转24例(36.9%)。停药后4周进行Hp检测,52例Hp阳性者根除42例,根除率为80.8%。结论糖尿病并发消化性溃疡有其独特的病因及临床特点,溃疡发生率与糖尿病程有一定关系。
Objective To investigate the etiology, clinical features and treatment of peptic ulcer associated with diabetes mellitus. Methods The clinical data of 65 patients with diabetic peptic ulcer were analyzed retrospectively, including the electronic gastroscope examination, the detection of Helicobacter pylori (Hp) infection and pathological examination. Results of patients with peptic ulcer clinical symptoms of atypical cases, the incidence and severity of ulcer disease and the duration of diabetes related to the higher age of onset. Forty-one patients were cured in 41 cases (63.1%) and improved in 24 cases (36.9%). Four weeks after the drug withdrawal, Hp tests were performed. Among the 52 Hp positive patients, 42 were eradicated, and the eradication rate was 80.8%. Conclusions Diabetes complicated with peptic ulcer has its unique etiology and clinical features. The incidence of ulcer is related to the course of diabetes mellitus.