论文部分内容阅读
目的对非急性发作期哮喘病人CD4+CD25+调节性T细胞的含量水平进行临床观察。方法对60例非急性期哮喘患者按年龄分组,采用流式细胞仪检测CD4+CD25+调节性T细胞含量水平,与60例健康人进行比较,在不同年龄段间存在不同差异性。结果①4～19岁(少年组)P<0.05差异有显著性。②20～49年龄组(青年组):P>0.05差异无显著性。③50～70年龄组(老年组):P<0.05差异有显著性。结论哮喘的发作可能与患者体内CD4+CD25+调节性T细胞水平有关,值得进一步研究和探讨,为临床治疗哮喘病提供了新的依据和新的思路。
Objective To investigate the level of CD4 + CD25 + regulatory T cells in non-acute asthma patients. Methods Sixty non-acute asthmatic patients were divided into groups according to age. Flow cytometry was used to detect the level of CD4 + CD25 + regulatory T cells. Compared with 60 healthy controls, there were differences in different age groups. Results ① P <0.05 in 4 ~ 19 years old (juvenile group) was significantly different. ② 20 ~ 49 age group (youth group): P> 0.05 no significant difference. ③50 ~ 70 age group (elderly group): P <0.05 difference was significant. Conclusions The onset of asthma may be related to the level of CD4 + CD25 + regulatory T cells in patients. It is worth further study and discussion, which provides a new basis and new ideas for clinical treatment of asthma.