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难治性心衰就是经常规抗心衰治疗-即正性肌力药物、扩管药物、利尿剂治疗而症状不能缓解者。本研究探讨纳洛酮联合硫酸镁治疗难治性心衰的疗效。1 资料与方法1.1 对象病例选自近2年我科住院的心力衰竭(CHF)患者,常规抗心衰治疗1周症状无改善者列入本研究。男14例,女8例,年龄34～72岁,平均58岁。其中冠心病9例,扩张型心肌病7例,风心病2例,老年性瓣膜退行性变2例,高血压心脏病1例,心肌炎1例。
Refractory heart failure is a routine anti-heart failure treatment - that is, inotropic drugs, pipe-expanding drugs, diuretics and symptoms can not be alleviated. This study was to investigate the efficacy of naloxone combined with magnesium sulfate in the treatment of refractory heart failure. 1 Materials and Methods 1.1 Subjects selected from the recent 2 years hospitalized patients with heart failure (CHF), conventional anti-heart failure treatment for 1 week without improvement in symptoms were included in this study. 14 males and 8 females, aged 34 to 72 years, mean 58 years. Of which 9 cases of coronary heart disease, dilated cardiomyopathy in 7 cases, 2 cases of rheumatic heart disease, senile valvular degeneration in 2 cases, 1 case of hypertensive heart disease, myocarditis in 1 case.