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对３４例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者在用一般降糖治疗后血糖稳定时加用锌剂，检测补锌前后免疫功能和血清锌含量的改变。结果发现：糖尿病组红细胞受体花环（ＲＢＣ－Ｃ３ｂＲＲ），Ｔ淋巴细胞亚群（ＣＤ３，ＣＤ４，ＣＤ４／ＣＤ８）及血清锌均低于正常对照组（Ｐ＜０．０１），而ＣＤ８及红细胞免疫复合物花环（ＲＢＣ－ＩＣＲ）高于对照组（Ｐ＜０．０１）；经补锌治疗一月后，糖尿病组血清锌，ＲＢＣ－Ｃ３ｂＲＲ，ＲＢＣ－ＩＣＲ，ＣＤ３，ＣＤ４及ＣＤ４／ＣＤ８达正常值，ＣＤ８也接近正常。各指标治疗前后比较差异均有高度显著性（Ｐ＜０．０１）。提示ＮＩＤＤＭ患者存在不同程度的缺锌和免疫功能低下，补锌可作为糖尿病（ＤＭ）一种可行的辅助疗法
34 cases of non-insulin dependent diabetes mellitus (NIDDM) patients with general glycemic control after the stability of blood glucose plus zinc agent to detect changes in immune function before and after zinc supplementation and serum zinc levels. The results showed that RBC-C3bRR, T lymphocyte subsets (CD3, CD4, CD4 / CD8) and serum zinc in diabetic group were lower than those in normal control group (P <0.01) The levels of RBC-ICR, RBC-ICR, CD3, CD4 and CD4 / CD8 in the diabetic group were significantly higher than those in the control group (P <0.01) Normal, CD8 is also close to normal. The differences of each index before and after treatment were highly significant (P <0.01). Tip NIDDM patients with varying degrees of zinc deficiency and immune dysfunction, zinc supplementation can be used as a viable adjuvant therapy of diabetes (DM)