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[目的]研究老年2型糖尿病患者血糖波动对视网膜病变的影响。[方法]将某院2009年12月～2010年10月收治的92例老年2型糖尿病患者按照视网膜病变程度分为3组,眼底正常组35例、眼底渗出组30例及眼底增殖组27例,应用动态血糖监测系统对患者血糖进行连续监测,组间结果进行比较分析。[结果]眼底渗出组及眼底增殖组患者的总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)及糖化血红蛋白(HbA1C)均明显增高(P﹤0.05);眼底渗出组及眼底增殖组患者的平均血糖水平(MBG)、标准差(SD)、平均血糖波动幅度(MAGE)均明显增高(P﹤0.05),且随眼底病变程度逐渐增高(P﹤0.05)。[结论]老年2型糖尿病患者血糖波动对视网膜病变具有明显的临床影响,应严格控制患者血糖水平以减少视网膜病变的发生。
[Objective] To study the influence of blood glucose fluctuation on retinopathy in senile type 2 diabetic patients. [Methods] A total of 92 elderly patients with type 2 diabetes treated in our hospital from December 2009 to October 2010 were divided into 3 groups according to the degree of retinopathy. 35 cases of normal fundus, 30 cases of fundus exudation and 27 cases of fundus proliferation Cases, the application of dynamic glucose monitoring system for continuous monitoring of patients with blood glucose, the results were compared between groups. [Results] The levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and glycosylated hemoglobin (HbA1C) were significantly higher in fundus exudation group and fundus proliferative group (P <0.05) The mean blood glucose level (MBG), standard deviation (SD) and mean blood glucose fluctuation (MAGE) in proliferative group were significantly increased (P <0.05), and gradually increased with fundus lesions (P <0.05). [Conclusion] The fluctuation of blood glucose in elderly patients with type 2 diabetes has obvious clinical effect on retinopathy. The blood glucose level should be strictly controlled to reduce the occurrence of retinopathy.