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1958年Frod等首先发现急性白血病骨髓染色体约50％有异常改变,急性淋巴细胞性白血病(以下简称ALL)的染色体异常改变也在50％左右,其发生原因,迄今为肿瘤学家和遗传学家所重视。姐妹染色单体互换(简称SCE),为细胞周期动
In 1958, Frod et al. First found that about 50% of the bone marrow chromosomes of acute leukemia had abnormal changes. The chromosomal abnormalities in acute lymphoblastic leukemia (hereinafter referred to as ALL) were also changed by about 50%. The reason for the occurrence is so far an oncologists and geneticists Attention. Sister chromatid exchange (referred to as SCE), for the cell cycle