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目的探讨在甲亢肝损害患者中如何应用抗甲状腺药物治疗的方法。方法 A组30例保肝治疗同时应用抗甲状腺药物;B组30例单纯应用保肝药物治疗5~10 d后,待肝损害≤1.5倍正常值再进一步应用抗甲状腺药物。其余低碘饮食及补充维生素及普萘洛尔等治疗相同。共治疗4周,比较并观察甲功及肝损害变化。结果 A组大部分患者甲功逐渐好转最终恢复正常,同时肝损害逐渐减轻直至恢复正常范围;B组部分患者因抗甲状腺药物未同时应用,致甲功恢复时间相对较长延误治疗时间临床症状无改善,部分患者肝功无改善甚至加重。结论确诊是甲亢致肝损害后,可考虑保肝治疗同时尽早应用抗甲状腺药物治疗。
Objective To explore how to use antithyroid drugs in patients with hyperthyroidism and liver damage. Thirty patients in group A received anti-thyroid drugs while those in group A received anti-thyroid drugs while 30 patients in group B received hepatic drugs 5 to 10 days later. The rest of the low-iodine diet and vitamin supplements and propranolol and other treatment the same. A total of 4 weeks of treatment, comparison and observation of thyroid function and liver damage changes. Results In most of the patients in group A, the gradual improvement of thyroid function eventually returned to normal, and the liver damage gradually decreased until the normal range was recovered. In some patients in group B, the delay in the recovery of thyroid function was delayed due to the non-concurrent use of anti-thyroid drugs. Improve, some patients with liver function improved or even worse. Conclusion Diagnosis of hyperthyroidism caused by liver damage, hepatoprotective therapy can be considered at the same time as soon as possible anti-thyroid drug treatment.