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对４１６例病毒性肝炎患者进行了抗－ＨＣＶ及其它血清标志物检测，结果共发现５２例抗－ＨＣＶ阳性患者，其中单独抗－ＨＣＶ阳性占２３．０％，与ＨＢＶ感染占４０．４％，与ＨＢＶ、ＨＤＶ感染占９．６％。抗－ＨＣＶ在慢性活动型肝炎、肝硬化中的阳性率分别为３０．４％和２２．７％，明显高于急性肝炎和非甲非乙型肝炎中的阳性率（２．８％、１３．０％），提示ＨＣＶ在促使肝病慢性化及加重病情方面有重要作用。对抗－ＨＣＶ阳性患者外周血Ｔ淋巴细胞分型结果显示：各型丙肝息者ＣＤ＿３、ＣＤ＿４比例均下降，而ＣＤ＿８比例上升，表现为Ｔｈ细胞功能下降，Ｔｓ细胞功能增强，提示细胞免疫功能紊乱是丙肝患者高慢性化率的免疫学基础。
Anti-HCV and other serum markers were detected in 416 patients with viral hepatitis. A total of 52 anti-HCV positive patients were found, of which 23.0% were anti-HCV positive and 40.4% , With HBV, HDV infection accounted for 9.6%. The positive rates of anti-HCV in chronic active hepatitis and liver cirrhosis were 30.4% and 22.7%, respectively, which were significantly higher than those in acute hepatitis and non-A non-B hepatitis (2.8%, 13 .0%), suggesting that HCV plays an important role in the promotion of chronic liver disease and aggravate the disease. The result of T lymphocyte typing in peripheral blood of patients with anti-HCV positive showed that the proportion of CD_3 and CD_4 decreased in all kinds of hepatitis C patients, while the proportion of CD_8 increased, which showed that the function of Th cells decreased and the function of Ts cells increased, suggesting that cellular immune dysfunction was Immunological basis for high rates of chronic hepatitis C infection.