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目的对盐酸米多君和美托洛尔治疗儿童体位性心动过速综合征的临床疗效进行观察并对比。方法2012—2016年收治的共96例儿童体位性心动过速综合征患者,随机分为两组,每组48例,分别给予盐酸米多君和美托洛尔治疗,治疗3个月后比较两组疗效。结果治疗后,两组患者在平卧位心率、平卧及直立时的收缩压、舒张压均无显著性差异(P>0.05)。美托洛尔组的直立心率、心率差值以及症状评分均显著低于盐酸米多君组(P<0.05)。美托洛尔组的总有效率为87.50%,盐酸米多君组为70.83%,差异有统计学意义(P<0.05)。结论美托洛尔治疗儿童体位性心动过速综合征的疗效较好。
Objective To observe and compare the clinical efficacy of midodrine hydrochloride and metoprolol in the treatment of children with orthostatic tachycardia syndrome. Methods A total of 96 children with orthostatic tachycardia admitted to our hospital from 2012 to 2016 were randomly divided into two groups (n = 48 each), treated with midodrine hydrochloride and metoprolol respectively. After 3 months of treatment, Group efficacy. Results After treatment, there was no significant difference between the two groups in heart rate, supine and upright systolic and diastolic pressures (P> 0.05). The upright heart rate, heart rate difference and symptom scores of metoprolol group were significantly lower than those of midodrine hydrochloride group (P <0.05). Metoprolol group, the total effective rate was 87.50%, midodrine hydrochloride group was 70.83%, the difference was statistically significant (P <0.05). Conclusion Metoprolol is effective in treating orthostatic tachycardia in children.