论文部分内容阅读
[目的]观察人工肝支持治疗对重型肝炎患者肝功能的支持效果及安全性。[方法]34例早、中、晚期重型肝炎患者在综合治疗基础上给予人工肝支持治疗,观察人工肝支持治疗前后患者肝功能、肾功能、凝血酶原活动度、凝血时间、电解质、血常规及临床症状变化情况。[结果]34例重型肝炎患者进行人工肝支持治疗后,肝功能、凝血功能及临床症状明显改善,而对肾功能、电解质及血常规无明显影响;总有效率为76.5%,不良反应轻;治疗亚急性重肝早、中、晚期有效率分别为100%、88%、0%;慢性重肝有效率为42%。[结论]人工肝支持治疗重型肝炎患者不良反应轻,对肝功能有肯定的支持作用,尤其对早、中期患者支持效果更好。
[Objective] To observe the effect and safety of artificial liver support on liver function in patients with severe hepatitis. [Methods] 34 patients with early, middle and advanced severe hepatitis were treated with artificial liver support on the basis of comprehensive treatment. The liver function, renal function, prothrombin activity, coagulation time, electrolyte, blood routine And changes in clinical symptoms. [Result] The results showed that the hepatic function, coagulation function and clinical symptoms of 34 patients with severe hepatitis were significantly improved after treatment with artificial liver support, but had no significant effect on renal function, electrolytes and blood routine. The total effective rate was 76.5% and the adverse reactions were mild. The rates of early, middle and late treatment of subacute severe hepatitis were 100%, 88% and 0%, respectively. The effective rate of chronic severe hepatitis was 42%. [Conclusion] The patients with severe hepatitis treated with artificial liver support have the advantages of light adverse reactions and positive effects on liver function, especially in early and mid-term patients.