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维生素D水平变化与多发性硬化的发生有密切的关系,维生素D受体基因多态性与多发性硬化相关。维生素D的活性形式骨化三醇可以预防多发性硬化的模型——实验性变态反应性脑脊髓炎或阻断其进展。对维生素D进行深入研究,对寻找防治多发性硬化的新药具有重要意义。
The level of vitamin D is closely related to the occurrence of multiple sclerosis. The polymorphism of vitamin D receptor gene is associated with multiple sclerosis. The active form of vitamin D calcitriol can prevent multiple sclerosis model - Experimental allergic encephalomyelitis or block its progress. In-depth study of vitamin D, for the search for a new drug prevention and treatment of multiple sclerosis is of great significance.