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目的探讨适合于我国实际情况的铁剂治疗慢性肾功能衰竭贫血的方法。方法 41例维持性血液透析患者随机分为两组 ,分别口服右旋糖酐铁和肌肉注射聚麦芽糖氢氧化铁 ,两组均使用促红细胞生成素。结果在治疗后第 6、12周两组患者血红蛋白、红细胞压积、血清铁蛋白、血清铁和转铁蛋白饱和度水平比治疗前有显著提高 ,肌肉注射铁剂组比口服铁剂组指标升高更明显 ,差别有显著性。结论肌肉注射聚麦芽糖氢氧化铁治疗慢性肾功能衰竭贫血效果优于口服铁剂 ,是一经济、实用的补铁方法
Objective To explore the method of iron treatment for anemia of chronic renal failure suitable for our country. Methods A total of 41 patients with maintenance hemodialysis were randomly divided into two groups: oral iron dextran and intramuscular injection of polymaltose ferric hydroxide, respectively. Erythropoietin was used in both groups. Results The levels of hemoglobin, hematocrit, serum ferritin, serum iron and transferrin in the two groups were significantly increased at 6th and 12th week after treatment compared with those before treatment, and those in the iron injection group were higher than those in the oral iron group Clement more obvious, the difference was significant. Conclusion Intramuscular injection of polymaltose iron hydroxide is superior to oral iron in the treatment of anemia of chronic renal failure and is an economical and practical method of iron supplementation