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1989年Fiorentio等发现小鼠活化的TH2细胞产生的一种活性物质,后来证明是一种糖蛋白,可抑制TH1细胞的激活和细胞因子的产生,将其命名为细胞合成抑制因子(cytokine synthesis
In 1989, Fiorentio et al. Found that an active substance produced by mouse activated TH2 cells was later proved to be a glycoprotein which can inhibit TH1 cell activation and cytokine production and named it cytokine synthesis