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以进口司巴沙星片为试验药与国产洛美沙星片随机对照治疗急性细菌性感染59例,司巴沙星开放试验治疗皮肤软组织及肠道感染22例,共计81例。两药均每日口服1次,每次200mg,疗程7~14d,随机对照试验中试验药与对照药总有效率分别为93.3%与82.8%,细菌清除率分别为96.7%与92.9%,药物不良反应发生率分别为6.25%与6.67%。开放试验司巴沙星治疗皮肤软组织、肠道感染22例,临床有效率100%,细菌清除率100%,药物不良反应发生率13.64%
The imported sparfloxacin tablets as the test drug and the domestic Lomefloxacin tablets were used for the treatment of 59 cases of acute bacterial infections. The sparfloxacin open test was used to treat skin and soft tissue and intestinal infections in 22 cases, a total of 81 cases. The two drugs were taken orally once daily for 200mg for 7 to 14 days. The total effective rates of the test drug and the control drug in the randomized controlled trials were 93.3% and 82.8% respectively, and the bacterial clearance rates were 96.7 % And 92.9%, adverse drug reactions were 6.25% and 6.67% respectively. Open trial Spartaine in the treatment of skin and soft tissue, intestinal infections in 22 cases, the clinical efficiency of 100%, bacterial clearance rate of 100%, the incidence of adverse drug reactions 13.64%