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急性和慢性肝炎并发之皮肤损害,可能是肝病以外的独立表现或是肝病多系统的症状的组成之一.作者在2年内见到11例肝炎并发皮疹,有些病例皮疹是肝炎的最初表现,没有肝病的临床症状及体征,经过常规的肝功试验才查出肝炎.从皮肤病理的发现及免疫学检查,认为肝病并发皮疹,是由于免疫复合物介导的血管损伤所致.在临床上没有明显的肝功能不全的情况下,这些皮损的出现应警惕潜在肝病的可能.本组11例包括6例急性肝炎其中5例为乙型肝炎,5例慢性肝炎其中仅1例为乙型肝炎.(见表)9例皮疹发生在没有明显的肝病症状之前,肝病的类型与皮疹形态之间存在着明显的关系.荨麻疹、斑丘疹主要发生在急性肝炎,而慢性肝炎的皮疹多
Skin lesions associated with acute and chronic hepatitis may be an independent manifestation of liver disease or a multifactorial manifestation of liver disease The authors saw 11 cases of hepatitis complicated with rash in 2 years and in some cases the first manifestation of hepatitis with no evidence of hepatitis Hepatic disease clinical symptoms and signs, only after conventional liver function tests to detect hepatitis.From the discovery of skin pathology and immunological examination, liver disease complicated with rash is due to immune complex-mediated vascular injury caused by clinically not Obvious liver failure, the occurrence of these lesions should be alert to the potential of liver disease in this group of 11 patients, including 6 cases of acute hepatitis in which 5 cases of hepatitis B, 5 cases of chronic hepatitis, only 1 case of hepatitis B (See Table) Nine cases of rashes occurred before there were no obvious symptoms of liver disease, and there was a clear relationship between the type of liver disease and the morphology of the rash Urticaria, maculopapular mainly in acute hepatitis, and the rash in chronic hepatitis