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虽然大多数青少年慢性关节炎(JCA)的预后良好,但一小部分有全身性关节炎或多关节关节炎者,对联用非类固醇抗炎药(NSAIDs)和免疫抑制剂无效。这些患儿有可能得益于抑制自身反应性T细胞免疫疗法及借助于灌注幼稚的T细胞前体细胞而重获正常免疫能力的疗法。作者?
Although most patients with chronic juvenile arthritis (JCA) have a good prognosis, a small percentage of those with systemic or polyarticular arthritis are ineffective with combination of NSAIDs and immunosuppressive agents. It is possible for these children to benefit from therapy that suppresses autoreactive T cell immunotherapy and regains normal immunity by means of infusing naïve T cell precursors. Author?