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85例经病原检查确诊的有症状的贾第虫病患者中,男性37例,女性48例,分为3组治疗。第1组一次顿服甲硝咪唑2. 4克;第2组甲硝咪唑2. 4克分2天服;第3组一次顿服甲硝磺酰咪唑2克。这3组病例的感染时间分别为34. 9±14. 0天、29. 1士11. 2天及29. 6±8. 8天,出现症状的时间分别为22. 9±14. 3天、19. 8±10. 3天及21. 8±15. 0天。各组病人粪内的贾第虫包囊数无大差别。服药后随访2个月,停药后的第1、 2、4、 8周各复查粪便连续3天。复查871份粪便和30份十二指肠内容物。寄生虫学和临床上的疗效,第1组治愈13例/26例,第2组治愈24例/31例,第3组治愈26例/28例。以甲硝磺酰咪唑的疗效较好,药物副作用也较少,可推荐为单剂治疗贾第虫病的选用药物。
Among the 85 patients with symptomatic giardiasis diagnosed by pathogen examination, 37 were males and 48 were females, which were divided into 3 groups. Group 1 Dayton metronidazole 2,4-d; Group 2 metronidazole 2,4-g 2-day service; Group 3 Dayton clothing methyl sulfonyl imidazole 2 grams. The infection time of these 3 groups of patients were 34.9 ± 14.0 days, 29.1 ± 11. 2 days and 29.6 ± 8.8 days, the symptoms of the time were 22.9 ± 14.3 days , 19.8 ± 10.3 days and 21.8 ± 15.0 days. There was no significant difference in the number of giardia cysts in each group of patients. Follow-up after 2 months of medication, discontinuation of the 1st, 2, 4, 8 weeks after each review stool for 3 days. Review 871 feces and 30 duodenal contents. The first group was cured in 13 cases / 26 cases, the second group was cured in 24 cases / 31 cases, the third group was cured in 26 cases / 28 cases. Methyl sulfonyl imidazole efficacy is better, less side effects of drugs can be recommended for the treatment of giardiasis single drug selection.