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对人工发酵培育冬虫夏草进行了３项致突变试验，结果表明小鼠胸骨骨髓细胞微核试验和小鼠精子畸形试验实验组与阴性对照组之间未见显著性差异，而实验组与阳性对照组之间均有显著性差异。Ａｍｅｓ试验表明各剂量组均未诱发直接和间接致突变作用。实验证明人工发酵培育冬虫夏草对实验哺乳动物体细胞、生殖细胞及细菌均无致突变作用，不引起遗传损伤。
Three mutagenic experiments were carried out on the artificial fermentation of Cordyceps sinensis. The results showed that there was no significant difference between the experimental group and the negative control group in the micronucleus test of sternal bone marrow cells and the sperm abnormality test in mice, while the experimental group and the positive control group There are significant differences between. Ames test showed that each dose group did not induce direct and indirect mutagenic effects. Experiments show that artificial fermentation of Cordyceps sinensis experimental mammalian somatic cells, germ cells and bacteria have no mutagenic effect, does not cause genetic damage.