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多囊卵巢综合征(polycystic ovary syndrome,PCOS)是引起育龄妇女不孕的主要原因之一,临床上以月经稀发或闭经、不育、多毛、痤疮、肥胖和卵巢多囊性变为主要特征。近年来动物实验揭示出生前暴露于母体过高雄激素中,可导致雌性胎儿于青春期产生PCOS样改变,包括高雄激素血症、LH
Polycystic ovary syndrome (PCOS) is one of the major causes of infertility in women of childbearing age. Clinically, it is characterized by oligomenorrhea or amenorrhea, infertility, hirsutism, acne, obesity and polycystic ovary . In recent years, animal experiments reveal that prenatal exposure to maternal hyperandrogenism can lead to PCOS-like changes in puberty in female fetuses, including hyperandrogenism, LH