防治糖尿病性神经病变的新概念

• 作 者: 俞霭瑶
• 出 处: 新药与临床
• 发表日期: 1989年04期
• 关键词: 高血糖 乙内酰脲类 神经损害症状 醛糖还原酶 血糖浓度 异常代谢 传导异常 神经传导 糖代谢 神经病

近年来,山梨醇和肌醇在神经内异常代谢的了解,对糖尿病性神经损害获得重要进展,导致防治该病的新概念,本文对此异常代谢进行综述。 糖尿病性神经病变流行病学382例用胰岛素治疗的糖尿病人中有神经病变症状的占10.7%,有神经电传导异常的达80%,但临床上只是20%病人有神经损害症状和体征。

In recent years, the understanding of abnormal metabolism of sorbitol and inositol in nerves has made significant progress on diabetic nerve damage, leading to a new concept of prevention and treatment of this disease. This article reviews the abnormal metabolism. Epidemiology of Diabetic Neuropathy 382 insulin-treated diabetic patients have 10.7% of neurological symptoms and 80% of abnormal electrical nerve conduction defects, but only 20% of patients have clinically neurologically damaged symptoms and signs.