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目的观察应用抗生素序贯疗法对治疗小儿社区获得性肺炎(CAP)的临床疗效。方法选取医院收治的小儿社区获得性肺炎患儿152例,随机分为观察组和对照组,每组76例。对2组患儿均采取止咳、平喘、祛痰、吸氧等对症治疗,观察组采取抗生素序贯疗法进行治疗,对照组采取抗生素常规治疗,比较2组治疗方法的临床疗效、住院时间、住院费用、药物不良反应发生率情况。结果 2组总有效率比较差异无统计学意义(P>0.05);但观察组患儿的住院时间、治疗费用、药物不良反应发生率均优于对照组(P<0.05和P<0.01)。结论抗生素序贯疗法治疗小儿社区获得性肺炎疗效确切,可缩短住院时间,降低治疗费用和药物不良反应率,值得临床推广应用。
Objective To observe the clinical effect of sequential antibiotics treatment on children with community-acquired pneumonia (CAP). Methods A total of 152 children with community-acquired pneumonia admitted to the hospital were randomly divided into observation group and control group with 76 cases in each group. The two groups of children were taken symptomatic treatment of cough, asthma, expectorant, oxygen and other symptomatic treatment, the observation group to take antibiotic sequential therapy for treatment, the control group to take antibiotics conventional treatment, the clinical efficacy of two groups of treatment methods, hospital stay, Hospitalization costs, the incidence of adverse drug reactions. Results There was no significant difference in the total effective rate between the two groups (P> 0.05). However, the hospitalization time, treatment cost and adverse drug reaction rate in the observation group were better than those in the control group (P <0.05 and P <0.01). Conclusion Sequential antibiotics treatment of infantile community-acquired pneumonia curative effect is exact, can shorten the hospital stay, reduce the cost of treatment and adverse drug reaction rate, worthy of clinical application.