论文部分内容阅读
Objectives. We studied the implantation rate during IVF cycles according to th e prescription or not of antibiotics. Materials and methods. During a 5-month p eriod all the patients aged less than 38 years were randomized into two groups a ccording to an independent personal variable. In group 1 amoxicilline +clavuian ic acid 1g/125mg were administrated from the ovum pick-up day for 6 days. In th e group 2 no antibiotic treatment was administered. Results. The two groups were identical for all the criteria (type of stimulation, IVF/ICSI report, indicatio ns, average age). The average number of collected oocytes, obtained embryos and transferred embryos was similar in the two groups. The implantation rate per tra nsfer was similar in the two groups (36.9%versus 36.5%; P>0.95). The pregnancy loss rate (biological pregnancy, early and late miscarriages or extra uterine p regnancy) was increased in a non significant manner (P=0.15) in the group with a ntibiotic: 33.3%(16/48) versus 20.8%(11/53) in the group without antibiotic. C onclusion. This prospective randomised study leads us not to recommend this anti biotic prescription at the time of the embryo transfer during in vitro fertilisation attempt.
Objectives. We studied the implantation rate during IVF cycles according to th e prescription or not of antibiotics. Materials and methods. In group 2 am antibiotic treatment was administered. The two groups were identical for all the criteria (type of stimulation, IVF / ICSI report, indicatio ns, average age). The average number of collected oocytes, embryos and transferred embryos was similar in the two groups. The implantation rate per tra nsfer was similar in the two groups (36.9% versus 36.5%; P> 0.95). The pregnancy loss rate (biological pregnancy, early and late miscarriages or extra uterine p regnancy) was increased in a non significant manner (P = 0.15) in the group with a ntibiotic: 33.3% (16 / 48) versus 20.8% (1 1/53) in the group without antibiotic. C onclusion. This prospective randomized study leads us not to recommend this anti biotic prescription at the time of the embryo transfer in in vitro fertilization attempt.