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目的探讨食管肿瘤患者气管插管全麻术后肺部感染的病原菌、危险因素和耐药性。方法选取2011年1月至2013年4月间收治的48例食管肿瘤气管插管全麻术后肺部感染患者作为观察组,选取同期45例食管肿瘤气管插管全麻术后无肺部感染者为对照组,分析病原菌、危险因素和耐药性情况。结果食管肿瘤气管插管全麻术后肺部感染以革兰氏阴性菌为主,对亚胺培南、泛生舒复耐药性低,其与基础疾病、气管插管置留时间、住院时间、术后镇痛、无菌操作、术后抗生素应用和术后激素应用有关(P<0.05)。结论食管肿瘤患者气管插管全麻术后肺部感染的影响因素众多,在临床上要规范操作气管插管且对症处理。
Objective To investigate the pathogens, risk factors and drug resistance of pulmonary infection after tracheal intubation general anesthesia in esophageal cancer patients. Methods Forty-eight patients with pulmonary infection underwent general anesthesia for esophageal cancer after tracheal intubation from January 2011 to April 2013 were selected as the observation group. Forty-five patients with esophageal cancer underwent tracheal intubation general anesthesia without pulmonary infection For the control group, analysis of pathogens, risk factors and drug resistance. Results Esophageal cancer endotracheal intubation after general anesthesia with Gram-negative lung-based infections, imipenem, low resistance to pan-mesenteric syphilis, and its underlying diseases, intubation residence time, hospital stay, Postoperative analgesia, aseptic manipulation, postoperative antibiotic use and postoperative hormonal application (P <0.05). Conclusion There are many influencing factors of lung infection after tracheal intubation general anesthesia in patients with esophageal cancer, and tracheal intubation and symptomatic treatment should be regulated in the clinical practice.