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1. 芳酰异硫氰与酚类作用时,反应一般以两种类型进行,即酰化与加成。某些情况下酰化反应占优势。但是硝基酚能够顺利地与芳酰异硫氰起加成反应。所得到的酰氨基硫代甲酸酚酯均为有一定熔点的良好晶体。2. 鄰氨基酚与芳酰异硫氰作用时,由氨基起加成反应得到对应的芳酰基硫脲。3. 含活泼亚甲基的化合物,如乙酰乙酸乙酯及丙二酸二乙酯,与对溴苯甲酰异硫氰作用时,可以得到亚甲基上活泼氢原子与试剂起加成反应的产物。
1. Aroyl isothiocyanates and phenols role, the reaction is generally two types, namely, acylation and addition. Acylation is dominant in some cases. However, nitrophenols smoothly reacted with aroylisothiocyanates. The resulting amidothioic acid phenols are all good crystals with a certain melting point. 2 o-aminophenol and aroyl isothiocyanates role, the reaction from the amino group to give the corresponding aroyl thiourea. 3. With active methylene compounds, such as ethyl acetoacetate and diethyl malonate, and the role of p-bromobenzoyl isothiocyanate, you can get the active hydrogen atoms on the methylene and reagents from the additive reaction Of the product.