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[目的]观察葛根素联合纳洛酮治疗椎基底动脉供血不足疗效。[方法]使用随机平行对照方法,将40例住院患者按随机数字表法随机分为两组。对照组20例口服阿司匹林,0.4mg/次,3次/d。治疗组20例葛根素,0.4mg/次,1次/d,静滴;纳洛酮,0.8mg/次,1次/d,静滴。均连续治疗20d为1疗程。观测临床症状、体征、不良反应。连续治疗2疗程,判定疗效。[结果]治疗后,治疗组痊愈10例,显效5例,有效2例,无效1例,总有效率95.00%。对照组痊愈8例,显效4例,有效1例,无效7例,总有效率65.0%。治疗组疗效优于对照组(P<0.05)。[结论]葛根素联合纳洛酮治疗椎基底动脉供血不足效果显著,值得推广。
[Objective] To observe the curative effect of puerarin and naloxone on vertebrobasilar insufficiency. [Methods] Using randomized parallel control method, 40 inpatients were randomly divided into two groups according to random number table method. Control group, 20 cases of oral aspirin, 0.4mg / time, 3 times / d. Treatment group, 20 cases of puerarin, 0.4mg / time, 1 / d, intravenous; naloxone, 0.8mg / time, 1 / d, intravenous infusion. Continuous treatment of 20d for a course of treatment. Observation of clinical symptoms, signs, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] After treatment, the treatment group cured 10 cases, markedly effective in 5 cases, effective in 2 cases, ineffective in 1 case, the total effective rate was 95.00%. In the control group, 8 cases were cured, 4 cases were markedly effective, 1 effective, 7 ineffective, and the total effective rate was 65.0%. The treatment group was better than the control group (P <0.05). [Conclusion] puerarin combined with naloxone is effective in treating vertebrobasilar insufficiency. It is worth promoting.