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测定7 例慢性 H B V 携带者 H B V 基因组全序列,经同源性比较,确定基因型。2 例基因型为 B 型,余均为 C 型;血清型adr 4 例,adw 3 例。各序列间 X 基因差异最大。未见 A1896 、 T1762 A1764等重要位点的变异。结合已有的2 株 H B V 中国流行株全基因序列,初步建立以中国流行株序列为基础的 H B V 标准序列,该标准序列与国外标准序列仅有22 个位点的差异
The sequence of H B V genome of 7 chronic H B V carriers was determined. The homology was compared to determine the genotype. Two cases of genotype B, the remaining are C type; serological adr 4 cases, adw 3 cases. X genes among the sequences of the largest differences. No A1896, T1762 A1764 and other important sites of variation. Based on the complete genome sequences of two H B V strains in China, the H B V standard sequence based on the Chinese popular strain sequence was initially established. This standard sequence has only 22 loci differences with foreign standard sequences