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胃癌是我国目前最常见的恶性肿瘤之一,微转移是恶性肿瘤在发展过程中所形成的尚处于临床不可探测阶段的微小转移灶,播散并存活于淋巴系统、血液循环、骨髓、肝、肺等组织器官中,是恶性肿瘤复发和转移的根源。目前对胃癌淋巴结微转移的深入研究主要集中在通过寻找不同的检测方法、途径和特异性肿瘤标志物,对常规检查淋巴结为阴性的胃癌,微转移检测可能对准确地确定临床分期、指导治疗、判断预后有积极临床意义。现就胃癌微转移检测研究的现状和存在的问题予以综述。
Gastric cancer is one of the most common malignant tumors in our country. Micrometastasis is a tiny metastasis of malignant tumor which is still undetectable in clinical development. It disseminates and survives in the lymphatic system, blood circulation, bone marrow, liver, Lung and other tissues and organs, is the root cause of recurrence and metastasis of malignant tumors. At present, the further research on micrometastasis of gastric cancer mainly focuses on the detection of different detection methods, pathways and specific tumor markers, the routine examination of lymph nodes negative for gastric cancer, micrometastasis detection may accurately determine the clinical stage, guide the treatment, To determine the prognosis has a positive clinical significance. Now on the detection of gastric cancer micrometastasis status and existing problems are reviewed.