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目的分析超敏C反应蛋白(hs-CRP)和冠状动脉(冠脉)狭窄程度及支架术后再狭窄相关性。方法 53例行经皮冠状动脉支架置入术患者,对比术前、术后hs-CRP含量,并分析hs-CRP和冠脉狭窄程度及支架术后再狭窄相关性。结果本组术前三支、双支及单支病变hs-CRP含量对比差异有统计学意义(P<0.05);术后双支、单支多处病变hs-CRP含量变化大,三支hs-CRP含量变化不显著,单支局限性病变变化不显著;1年后冠脉造影复查再狭窄发生率(3.57%)显著低于支架内再狭窄发生率(16.00%)(P<0.05)。结论 hs-CRP与冠脉内狭窄程度显著相关,且与单支病变相比,多支病变hs-CRP显著显升高,hs-CRP可作为预测术后出现再狭窄重要指标。
Objective To analyze the correlation between hs-CRP and coronary artery (stenosis) and the degree of restenosis after stenting. Methods Fifty-three patients underwent percutaneous coronary stenting were enrolled in this study. The levels of hs-CRP in preoperative and postoperative patients were compared. The correlation between hs-CRP, coronary stenosis and the degree of coronary artery stenosis was analyzed. Results There were significant differences in hs-CRP levels between the two groups before and after single-vessel multiple lesion (P <0.05) There was no significant change in the content of -CRP, and the limitation of single branch was not significant. The incidence of restenosis after coronary angiography at 1 year (3.57%) was significantly lower than that of in-stent restenosis (16.00%) (P <0.05). Conclusion The hs-CRP is significantly correlated with the degree of coronary stenosis. Compared with single-vessel lesion, hs-CRP is significantly increased in multi-vessel disease. Hs-CRP can be used as an important index in predicting postoperative restenosis.