The natural design for the generation and the fate of proteins in an organism could be as complicated as life itself.A protein is biosynthesized strictly accord
Mammalian target of rapamycin (mTOR) plays essential roles in cell proliferation,survival and metabolism by forming at least two functional distinct multi-prote
Pulmonary hypertension (PH) is a potentially lethal disorder because of a dearth of effective therapeutic options (Schermuly et al., 2011;Mehari et al., 2014).P
Dear Editor,Glutaredoxins (Grxs) are glutathione-dependent thiol disulfide oxidoreductases of the thioredoxin family present in all organisms from bacteria to h
As a famous Chinese saying goes,"A jouey of a thousand miles begins with a single step".It teaches us that perseverance and steadfastness are absolutely essenti
Tightly controlled extracellular matrix (ECM) homeostasis and remodeling is critical for normal organ homeostasis,wound healing and tissue repair.However,excess