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目的:分析戈舍瑞林(Goserelin)联合腹腔镜手术治疗子宫内膜异位症(Endometriosis,EMT)的治疗效果。方法:将88例EMT患者分成二组:Goserelin治疗组(n=48),腹腔镜手术前,患者每4周皮下注射Goserelin(3.6mg,3 months);未用药组(对照组)40例,腹腔镜手术未用药。术后,两组患者均随访3～9months,记录并比较两组治疗的术中一般情况及术后治疗的有效率、复发率。结果:Goserelin治疗组治疗有效率(95.7%)较对照组高(78.9%)(P<0.05),Goserelin治疗组9个月复发率(10.6%)低于对照组(28.9%)(P<0.05)。结论:Goserelin联合腹腔镜手术治疗EMT,腹腔镜术中出血少,手术操作时间短,术后恢复较快,药物手术结合治疗具有有效率高、副反应小、复发率低等优点。
Objective: To analyze the therapeutic effect of Goserelin combined with laparoscopic surgery on endometriosis (EMT). Methods: 88 patients with EMT were divided into two groups: Goserelin treatment group (n = 48). Before laparoscopic surgery, Goserelin (3.6 mg, 3 months) was injected subcutaneously every 4 weeks in 40 patients, Laparoscopic surgery without medication. After operation, both groups were followed up for 3 ~ 9months. The general intraoperative conditions and the effective rate and recurrence rate of the two groups were recorded and compared. Results: The Goserelin treatment group (95.7%) was higher than the control group (78.9%) (P <0.05), and the Goserelin treatment group was lower than the control group (28.6%) at 9 months (10.6%, P <0.05) ). Conclusion: Goserelin combined with laparoscopic surgery for EMT has the advantages of less bleeding, shorter operation time and faster postoperative recovery. The combination of drug and operation has the advantages of high efficiency, low side effects and low recurrence rate.