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目的观察5-氨基酮戊酸光动力疗法(ALA-PDT)治疗尖锐湿疣的临床疗效。方法将55例尖锐湿疣患者分为两组,试验组(26例)采用ALA-PDT治疗,对照组(29例)采用液氮冷冻治疗,并于末次治疗后12周进行疗效评估,比较两组治疗后的复发状况。结果试验组和对照组治愈率分别为76.9%和48.3%,复发率分别为23.1%和51.7%,试验组和对照组复发率比较,差异有统计学意义(P<0.05)。结论 5-氨基酮戊酸光动力疗法治疗尖锐湿疣疗效高,可显著降低复发率。
Objective To observe the clinical efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of condyloma acuminatum. Methods 55 patients with condyloma acuminatum were divided into two groups. The experimental group (26 cases) was treated with ALA-PDT. The control group (29 cases) was treated with liquid nitrogen freezing. The curative effect was evaluated 12 weeks after the last treatment. Recurrence after treatment. Results The cure rate of experimental group and control group were 76.9% and 48.3% respectively, the recurrence rates were 23.1% and 51.7% respectively. There was significant difference between the experimental group and the control group (P <0.05). Conclusion 5-aminolevulinic acid photodynamic therapy for the treatment of condyloma acuminata high efficacy, can significantly reduce the recurrence rate.