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目的:文章主要就阿莫西林所致不良反应及药学临床分析进行探究,以期为该药物合理使用提供一定参考。方法:采取随机选择某院2015年7月至2016年7月该时间中因使用阿莫西林而产生不良反应的80例患者为研究对象,随后通过对他们药物服用量、时间以及所出现不良反应症状等临床资料进行回顾性研究以此探究阿莫西林不良反应药学原理。结果:通过对80例患者回顾性研究可知:(1)80例患者中在使用阿莫西林出现不良反应时间段中,最高为7d内比例高达47.5%(38/80);(2)患者阿莫西林使用途径所诱发不良反应中口服以65%(52/80)而高于静脉滴注35%(28/80);(3)阿莫西林过敏性不良反应发生率最高,达52.5%(42/80);(4)80例阿莫西林不良反应患者经治疗后,治愈率为97.5%(78/80)。另外,上述对比差异构成统计学意义(P<0.05)。结论:阿莫西林用药中除了要充分结合患者病情实际给予准确量以及选择适宜途径外,还需要密切观察其症状,以此在第一时间采取有效措施进行处理。
Objective: The article mainly investigates the adverse reactions caused by amoxicillin and the clinical analysis of pharmacy, in order to provide some reference for the rational use of the drug. Methods: Totally 80 patients who were randomly selected from the hospital from July 2015 to July 2016 due to the use of amoxicillin were enrolled in this study, and then their medication dosage, time and the adverse reactions Symptoms and other clinical data retrospective study to explore the amoxicillin side effects of pharmacological principles. Results: The retrospective study of 80 patients showed that: (1) In the 80 patients, the highest proportion was 47.5% (38/80) within 7 days after amoxicillin was adverse reaction; (2) The incidence of side effects caused by the use of moxillin was 65% (52/80) higher than that of intravenous drip (35%) (28/80). (3) The incidence of allergic reactions to amoxicillin was the highest (52.5% 42/80); (4) 80 cases of amoxicillin adverse reactions after treatment, the cure rate was 97.5% (78/80). In addition, the above-mentioned contrast differences constitute a statistical significance (P <0.05). Conclusion: Amoxicillin medication in addition to the full combination of patients with the actual situation to give the exact amount and select the appropriate way, but also need to closely observe the symptoms, in order to take effective measures to deal with the first time.