论文部分内容阅读
作者用马抗人胸腺细胞球蛋白(horse anti-human thymocyte globulin,ATG)和男性激素治疗54例重症再生障碍性贫血.全部患者皆接受标准的支持疗法,包括:输红细胞、血小板,发热、粒细胞≤500/mm~3时静脉输注广谱抗生素。通常使红细胞压积维持于25～30%,血小板数≥20,000/mm~3,仅1例输过粒细胞。行隔离措施。治疗前所有患者行1:1,000的正常马血清和1:1,000的马 ATG 的皮内试验均阴性。静脉给予 ATG16mg/kg/d,共10天,每天量稀释于生理盐水1,000～
The authors treated 54 patients with severe aplastic anemia with horse anti-human thymocyte globulin (ATG) and male hormones. All patients received standard supportive care including: transfusion of red blood cells, platelets, fever, Intravenous infusion of broad-spectrum antibiotics when cells ≤500 / mm ~ 3. Usually hematocrit maintained at 25 to 30%, platelet count ≥ 20,000 / mm ~ 3, only 1 case of transfusions. Line isolation measures. Before treatment, all patients were negative with 1: 1,000 normal horse serum and 1: 1,000 horse ATG. ATG given intravenously 16mg / kg / d, a total of 10 days, daily dilution in saline 1,000 ~