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目的 通过对子宫乳头状浆液性癌的临床病理特征的分析 ,探讨其合理的治疗方法。方法 自 1983年 1月至 1998年 6月 ,我院收治子宫乳头状浆液性癌 16例 ,对其临床病理、治疗及预后进行回顾性研究。结果 全部病例采用手术治疗 ,术后辅助放疗和 /或化疗者 14例。 5 6.2 %的病例肌层浸润深度超过 1/ 2肌层 (9/ 16) ,62 .5 %有宫外扩散(10 / 16) ,淋巴结转移率 62 .5 % (5 / 8) ,几乎缺乏雌、孕激素受体。预后差 ,随访期内 9例死亡。结论 子宫乳头状浆液性癌有其独特的临床病理特征 ,与普通的子宫内膜癌明显不同 ,合理的个体化综合治疗可延长生存期。
Objective To analyze the clinical and pathological features of uterine papillary serous carcinoma and discuss its reasonable treatment. Methods From January 1983 to June 1998, 16 cases of uterine papillary serous carcinoma were treated in our hospital. The clinical pathology, treatment and prognosis were retrospectively studied. Results All the cases were treated by surgery, and postoperative adjuvant radiotherapy and / or chemotherapy were performed in 14 cases. Myometrial invasion was more than 1/2 of myometrium in 6.2% (62 cases), 62.5% (10/16) in myometrium, 62.5% (5/8) in lymph node metastasis, almost lacking Estrogen and progesterone receptors. Poor prognosis, 9 patients died during the follow-up period. Conclusion Uterine papillary serous carcinoma has its unique clinicopathological features, which are obviously different from those of ordinary endometrial carcinoma. The rational individualized comprehensive treatment can prolong the survival period.