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肿瘤的导向治疗已研究多年,但临床实验提示静脉使用免疫偶联物对实体瘤的治疗效果因多种原因并不理想。局部使用免疫偶联物在理论上有助于克服这些原因而获得成功。膀胱癌因其独特的解剖及生物学特性而成为这一思路的良好模型。本文试对近年国内外免疫偶联物膀胱灌注的研究及进展进行综述
Guided treatment of tumors has been studied for many years, but clinical trials suggest that the therapeutic effect of intravenous immunoconjugates on solid tumors is not ideal for a variety of reasons. Topical use of immunoconjugates has theoretically helped to overcome these causes. Bladder cancer is a good model for this idea because of its unique anatomy and biological properties. This article reviews the research and progress of immunoconjugates bladder irrigation at home and abroad in recent years