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目的分析药品不良反应(adverse drug reaction,ADR)发生的规律及特点,为临床合理用药及药物安全性评价提供依据。方法对我院2004-2006年332例ADR报告进行分类统计和分析。结果ADR,以抗感染药最多,其次是中成药、心血管类。ADR病例中以静脉用药为主。主要的ADR类型为皮肤损害、消化系统损害等。结论应加强ADR监测,以减少和避免ADR的发生,保证用药安全性。
Objective To analyze the rules and characteristics of adverse drug reaction (ADR) and provide basis for clinical rational drug use and drug safety evaluation. Methods 332 cases of ADR from 2004 to 2006 in our hospital were classified and analyzed. Results ADR to anti-infectives up, followed by proprietary Chinese medicines, cardiovascular class. ADR cases in the main intravenous medication. The main types of ADR are skin lesions, digestive system damage and the like. Conclusion ADR monitoring should be strengthened to reduce and avoid the occurrence of ADR and ensure the safety of medication.