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目的分析蚌埠市儿童青少年代谢综合征(MS)流行情况及其危险因素,为成年期疾病的早期预防提供依据。方法根据蚌埠市2007年中小学生身高、体重体检结果进行体重正常、超重和肥胖学生的筛选,随机抽取921名7～18岁学生进行身高、体重、腰围、臀围、血压测量,同时采集空腹时静脉血测定血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和空腹血糖(FPG)、尿酸(UA)、超敏C反应蛋白(hs-CRP),并进行甲状腺B超检查。结果 3组学生MS检出率为肥胖组(28.4%)>超重组(11.9%)>正常体重组(1.7%),差异有统计学意义。除TC外,MS各危险因素及其他检测项目均数在MS组和非MS组之间差异均具有统计学意义(P值均<0.01)。MS各危险因素异常检出率在MS组与非MS组之间差异有统计学意义(P值均<0.01)。MS各组分检出率以中心性肥胖最常见,其次为高三酰甘油和高血压。结论随着儿童青少年体质量指数的增加,MS及各危险因素检出率显著增加。加强对儿童青少年MS指标监测已成为预防心血管疾病的必要措施。
Objective To analyze the prevalence and risk factors of metabolic syndrome (MS) in children and adolescents in Bengbu, and provide evidence for early prevention of adult diseases. Methods Nine hundred and seventy students (7-18 years old) were randomly selected for height, weight, waist circumference, hip circumference and blood pressure measurement according to the height and weight examination results of 2007 primary and secondary school students in Bengbu. At the same time, fasting Venous blood was collected for the determination of serum total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and fasting blood glucose (FPG) High-sensitivity C-reactive protein (hs-CRP), and thyroid ultrasound B-check. Results The detection rate of MS was significantly higher in obese group (28.4%) than in overweight group (11.9%) and normal weight group (1.7%). In addition to TC, the mean number of MS risk factors and other test items was significantly different between MS and non-MS groups (P <0.01). MS detection of abnormalities in risk factors in the MS group and non-MS group differences were statistically significant (P all <0.01). MS detection rate of each component to the most common central obesity, followed by hypertriglyceride and hypertension. Conclusion With the increase of body mass index of children and adolescents, the detection rate of MS and various risk factors increased significantly. Strengthening MS monitoring of children and adolescents has become a necessary measure to prevent cardiovascular disease.