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目的观察双歧杆菌活菌制剂治疗新生儿母乳性黄疸的疗效。方法对83例新生儿母乳性黄疸患儿随机分为双歧杆菌治疗组和常规治疗组,常规治疗组采用输液、白蛋白静点,重症采用蓝光治疗;双歧杆菌治疗组在常规治疗方法基础上加用双歧杆菌活菌制剂,并观察两组患儿黄疸消退时间及血清总胆红素水平的变化。结果双歧杆菌治疗组和常规治疗组黄疸消退时间分别为(4.2±2.3)、(5.7±2.7)d,两组比较有显著性差异(P<0.05),治疗5d血清总胆红素值分别为(45.8±17.5)、(82.7±32.8)umol/L,两组比较有显著性差异(P<0.01)。结论双歧杆菌活菌制剂治疗新生儿母乳性黄疸有显著疗效。
Objective To observe the efficacy of live bifidobacterium preparation in the treatment of neonatal breast milk jaundice. Methods 83 cases of neonatal breast milk jaundice were randomly divided into bifidobacterium treatment group and conventional treatment group, conventional treatment group infusion, albumin static point, severe blue light treatment; Bifidobacterium treatment group based on conventional treatment methods Add Bifidobacterium viable preparations, and observe the changes of jaundice in both groups and serum total bilirubin levels. Results The regression time of jaundice in the Bifidobacterium group and the conventional treatment group was (4.2 ± 2.3) and (5.7 ± 2.7) days respectively, there was significant difference between the two groups (P <0.05). The serum total bilirubin value (45.8 ± 17.5) and (82.7 ± 32.8) umol / L, respectively, with significant difference between the two groups (P <0.01). Conclusion Bifidobacterium viable preparations have a significant therapeutic effect on neonatal jaundice.